How to Get Rid of Frown Lines Between Eyebrows Naturally

Those vertical lines between your eyebrows—sometimes called “11 lines” because they often appear as two parallel creases—can make you look…
Serene woman showing relaxed brow lines, potentially achieved with Glownetics botox in a bottle for smoother skin.

Those vertical lines between your eyebrows—sometimes called “11 lines” because they often appear as two parallel creases—can make you look perpetually angry or worried. Even when you’re perfectly content.

Botox is the quick fix, but if you’d rather avoid needles, here’s how to genuinely soften frown lines at home.

Why Frown Lines Are Stubborn

The muscles between your eyebrows (corrugator supercilii, if you want to get technical) are remarkably strong and active. You use them when you concentrate, squint at screens, express concern, react to bright light, and even sleep (many people unconsciously furrow their brow at night).

This constant contraction creates deep creases that eventually stay even when your face is relaxed. Unlike crow’s feet or forehead lines, frown lines often become quite deep because of how powerfully these muscles contract.

💡The Challenge
Frown lines form from some of the strongest, most active muscles on your face. That’s why they can be stubbornly deep—and why effective treatment needs to actually address muscle activity, not just hydrate or plump the surface.

The Muscle-Relaxing Solution

Since frown lines are created by muscle contraction, the most effective approach is reducing that contraction. This is exactly what Botox does—and what topical alternatives can do more gradually.

Argireline: The Key Ingredient

Argireline (acetyl hexapeptide-8) is your primary weapon against frown lines. It works by interfering with the nerve signals that tell your corrugator muscles to contract.

With consistent twice-daily application directly to the frown line area, argireline progressively relaxes these muscles, allowing the creases to soften over time.

The Glow Filler kit is designed specifically for this—concentrated argireline serum plus microneedling for enhanced delivery to these stubborn lines.

Application Technique for Frown Lines

These lines benefit from targeted, consistent application:

Morning and night: After cleansing, apply a small amount of argireline serum directly to the frown line area. Use your ring finger to tap it in gently—don’t rub or stretch the skin.

Let it absorb: Give the serum a minute before applying other products. The peptide needs direct skin contact to work.

Be patient: Frown lines didn’t form overnight and won’t disappear overnight. Expect gradual softening over 4-8 weeks.

More isn’t necessarily better. Apply enough to cover the area thoroughly, but excessive amounts just waste product. Twice-daily application at the right concentration is what matters, not piling on extra layers.

Microneedling for Deeper Results

For stubborn frown lines, microneedling can make a significant difference. Those micro-channels allow argireline to penetrate deeper into the tissue where the muscles actually are.

Weekly protocol:

Apply argireline serum to the frown line area. Microneedle the area with 0.25-0.5mm needles using gentle stamping motions. Apply more serum after treatment. Leave overnight without washing.

The combination of daily topical argireline plus weekly microneedling-assisted delivery can achieve results approaching professional treatment levels.

Technique Tip
When microneedling the frown line area, stamp perpendicular to the lines themselves. This creates channels that cross the creases, allowing serum to penetrate into the depth of the wrinkle.

Supporting Treatments

While argireline handles the muscle component, supporting ingredients address skin quality:

Retinol

Retinol stimulates collagen production, helping the skin bounce back from creasing. Use on non-microneedling nights. The Glow Retinol Serum includes niacinamide to reduce potential irritation.

Peptide Serums

Signal peptides like matrixyl tell your skin to produce more collagen. Combined with argireline, you’re both relaxing muscles and rebuilding skin structure.

Sunscreen

UV damage breaks down collagen and worsens all wrinkles. Daily SPF is non-negotiable for any anti-wrinkle effort.

Lifestyle Factors for Frown Lines

Products can only do so much if you’re constantly reinforcing the lines:

Screen positioning: If you’re squinting at your computer or phone, raise the screen, increase text size, or get your eyes checked. Constant squinting deepens frown lines.

Sunglasses: Bright light makes you squint. Quality sunglasses reduce frown muscle activation throughout the day.

Stress management: Chronic stress keeps tension in your face. Notice when you’re furrowing unconsciously and consciously relax those muscles.

Sleep position: Face-down sleeping can compress the frown line area. Try to keep pressure off your forehead.

FactorWhy It MattersSolution
Screen squintingConstant corrugator activationAdjust screens; check vision
Bright lightTriggers squinting reflexWear sunglasses
Stress tensionUnconscious furrowingAwareness; relaxation techniques
Sleep positionCompresses creasesBack sleeping; silk pillowcase

What Results Can You Expect?

Let’s be realistic about what at-home treatment can achieve for frown lines:

Fine frown lines: Can be significantly softened, sometimes nearly eliminated with consistent treatment.

Moderate frown lines: Noticeable softening and reduced depth. Lines may still be visible but much less prominent.

Deep, etched frown lines: Will soften but won’t disappear completely. At-home treatment can reduce their severity and prevent further deepening.

Starting early (prevention) is always easier than treating deep, established lines. If you’re noticing frown lines beginning to form, now is the ideal time to start treatment.

The Complete Frown Line Protocol

Daily Morning: Cleanse → Argireline serum (focus on frown area) → Moisturizer → SPF + sunglasses

Daily Evening (non-microneedling nights): Cleanse → Argireline serum → Retinol → Moisturizer

Weekly (microneedling night): Cleanse → Argireline serum → Microneedle frown area → More serum → Hydrating moisturizer (skip retinol)

Ongoing: Awareness of furrowing habits, sunglasses in bright light, stress management

Most people notice initial softening at 3-4 weeks. Significant improvement typically occurs at 6-8 weeks. Maximum results develop over 2-3 months with consistent daily use and weekly microneedling.

When to Consider Professional Treatment

At-home treatment works well for prevention and moderate concerns. Consider professional consultation if your frown lines are very deep and don’t smooth when you relax your face, you’ve been consistent with home treatment for 3+ months without meaningful improvement, or you want more immediate or dramatic results.

Many people use at-home treatment to extend time between professional appointments, reducing both cost and frequency of injections.

The Bottom Line

Frown lines are stubborn because they’re caused by strong, active muscles. Effective treatment requires actually addressing that muscle activity—which is exactly what argireline does.

Combine consistent argireline application with weekly microneedling, supporting collagen-builders like retinol, and lifestyle adjustments to stop reinforcing the lines. Give it time, and those angry elevens can soften into something much more serene.

Your expression should reflect how you actually feel—not make you look worried when you’re not.

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